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Millions of humans face this undertaking despite living a healthy lifestyle

In kidney diseases, gentamicin can induce nephrotoxicity, leading to impaired renal function, while Riceberry bran extract (RBBE) can initiate protective mechanisms in the kidneys via regulation of the PKC/NRF2 antioxidant defense pathway [49]

1 Introduction Parkinsons disease (PD) is a chronic progressive and extensive degenerative disease of the extrapyramidal nervous system that can cause motor symptoms (tremor, muscle rigidity, bradykinesia/slow movements, and postural instability) as well as non-motor symptoms (neuro-vegetative, psycho-cognitive/dementia, pain/sensory, and/or sleep disturbances) ( Parkinsons disease is a multisystem disorder, a consequence of multi-neuropeptidergic dysfunction, which includes dopaminergic, serotoninergic, cholinergic, and noradrenergic systems

In aggregate, recent studies offered additional evidence on the association between elevated UA and CAD