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21,22 Another suggested hypothesis is that ethanol may directly enhance the activity of NAD(P)H:quinone reductase, serving to reconvert quinone metabolites back to native APAP and thereby limiting the accumulation of toxic metabolites

The malfunction of methylation in the developing brain due to inherited mutations, compounded by epigenetic stresses, underlies the pathological process of a variety of neurodevelopmental and/or psychiatric disorders, including diseases that manifest at different stages of life, such as MDD and SZ

Nutrients,2023:15(3),718

Patients taking medication for lifestyle-related comorbid diseases, such as hypertension, dyslipidemia, and diabetes, were included