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Smoking among those diagnosed with Crohns disease may increase the risk of flare ups, impede remission, and increase the overall severity of the condition necessitating more invasive treatments (Johnson 2005)

Fibroblast Growth Factor (FGF21) Fibroblast growth factor (FGF) 21, expressed primarily in the liver, but also found in adipose tissue, skeletal muscle, and pancreas, is a member of the FGF family and acts as a metabolic regulator of body weight, glucose metabolism, and lipid metabolism (237)