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Moreover, the primary function of glutathione peroxidase enzymes is to protect cells from oxidative damage by reducing peroxides and preventing their harmful effects

3.3 Environmental factors While diet and dietary additives such as pro-, pre and antibiotics play major roles in the formation of the gut microbiota, the water environment provides a complex and diverse living environment for aquatic animals with many important factors affecting the GM (Spanggaard et al., 2000)

Disease states, including iron-deficiency anemia (Ramachandran and Iyer, 1974), severe uremia, cirrhosis of the liver, and hypothyroidism lead to increased erythrocyte glutathione reductase activity