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This dual regulation highlights the intricate control of Chac1 expression, linking its transcriptional activation by stress signals to its proteasomal degradation, which is crucial for maintaining cellular homeostasis under stress conditions (Oh-hashi et al., 2013)

Accordingly, the HF6 and HF12 groups exhibited negligible levels of complex II - III activity (Figure 5C), the lower rates of respiration in state 3 (Figure 4A), the higher levels of ROS (Figure 7A) and lipid peroxidation (Figure 7B), and the worst outcomes in liver histology (Figure 3)

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6 Endometriosis has also been defined as a hormonal disease, an autoimmune disease, a/an (epi)genetic disorder, or due to environmental stimuli or nutritional deficiency