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Can L-Citrulline and L-Arginine Be Taken Together

doi: 10.1038/ijo.2015.237 152 KuroishiT

More specifically, a decrease in various cytokines such as interferon-gamma, IL-6, and IL-12p40 secretion, and an increase in IL-10 secretion was observed, along with low cell-activation status of antigen-presenting cells (APC) and an inhibition of IL-6 and IL-8 production by TLR2 and TLR4-stimulated monocytes in a dose-dependent manner

Such findings led scientists to label AOD-9604 as the worlds first drug with a metabolic mechanism of action for obesity meaning it works by accelerating fat metabolism rather than suppressing appetite