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However, although patients with PTSD have been found reduced GABAARs, the GABAergic system has weaker pharmacodynamics at the receptor level

MUC-1 is a tumor-associated antigen that is downregulated in IBD

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In recent studies using BRET (Bioluminescence Resonance Energy Transfert) or FRET (Fluorescence Resonance Energy Transfer) techniques, a large panel of opioid ligands were shown to have a different ability to both activate G proteins and recruit arrestins at MOR and DOR (Mcpherson et al., 2010