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Macrophages in different environments can be polarized into M1 (classical activation) and M2 (selective activation) two different phenotypes, M1 macrophages have pro-inflammatory effects, in the process of colitis occurrence and development of M1 macrophages polarization increases, causing a further increase in pro-inflammatory cytokines, while M2 has anti-inflammatory effects, can promote the secretion of anti-inflammatory factors, and is related to the resolution of inflammation [60]

Drg J, Godzialska A, Knapik-Czajka M, Matua A, Jakiewicz J

Las publicaciones mecansticas han examinado rutas como FAK-paxilina, VEGFR2-Akt-eNOS y produccin de xido ntrico