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10.1016/j.jnutbio.2019.02.006 63 PeiS.-N.LeeK.-T.RauK.-M.LinT.-Y.TsaiT.-H.HsuY.-C.et al (2024)

Interestingly, 8.7% of DEGs in the entire data set coded for mitochondrial proteins, which were generally downregulated (Supplementary Data 1)

The research demonstrates that NAD+ restoration addresses multiple hallmarks of aging simultaneously, positioning it as a cornerstone intervention for longevity medicine with applications ranging from neurodegenerative disease prevention to esthetic enhancement