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doi: 10.1038/s41419-018-1286-2 92 GhotbaddiniMCisseKCareyAPowellJB

Men with androgenic alopecia are more likely to have a higher baseline of free androgens

The apolipoprotein E4 genotype contributes to the abnormal accumulation of lipid droplets (LD) in microglia and the formation of neurotoxic LD-accumulating microglia, which are capable of directly inducing neuronal Tau phosphorylation and apoptosis, and the degree of LD accumulation is positively correlated with the severity of cognitive decline and pathology [148]

Vitamin D : After intestinal absorption, vitamin D3 (cholecalciferol) is transported to the liver, where it undergoes 25-hydroxylation by the enzyme CYP2R1 to form 25-hydroxyvitamin D [25(OH)D]