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Science 244 , 224226 (1989)

This finding is consistent with the analysis by Li et al ( Because ICIs are most commonly prescribed to older patients ( In several single-agent analyses, we observed strong safety signals, among which pulmonary embolism (PE) exhibited a particularly prominent association (ROR 3.20, 95% CI 2.114.81), suggesting that PE may represent a serious adverse event that warrants attention during ICI therapy

Journal of Agricultural and Food Chemistry 52: 8151-8154 (2004) Du Toit WJ, Lisjak K, Stander M, Prevoo D

In in vitro assays using peripheral blood mononuclear cells from patients with AS, it was demonstrated that cryptotanshinone and tanshinone IIA, the main compounds of SMR, significantly reduced the protein expression levels of COX-2, IL-6, and TNF-