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For conventional CD16 + NK cells, the association between CD38 and CD16 promotes the CD38-mediated activation of intracellular signaling pathways, resulting in the initiation of Ca 2+ flux, zeta-chain-associated protein kinase 70 (ZAP70) tyrosine phosphorylation, mitogen-activated protein kinase (MAPK) activation inducing IFN- secretion and cytotoxicity crucial for the immune response [47]

While both are copper peptides, AHK-Cu has a distinct amino acid sequence from GHK-Cu, meaning their exact biological activities and pharmacokinetics may differ

Beta-oxidation and beta-3 adrenergic signaling are selectively stimulated, enabling detailed studies of lipid metabolism and energy regulation

[email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers