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Potential side effects and the impact of chronic supplementation are areas that require more extensive investigation

The formation of free radicals in the body begins and increases with catabolic reactions as well as factors such as fatty diets, unhealthy nutrition, smoking, drug treatments, alcohol consumption, radiation, pesticides, and environmental pollution

For instance, omeprazole, a PPI, has been identified to block efflux pumps in gram-negative bacteria, making the bacteria sensitive again to antibiotics such as ciprofloxacin

This streamlined interaction highlights the potential of polyphenols to address multiple pathological mechanisms simultaneously, underscoring their promise as multitarget agents in combating complex diseases like AD