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When filaggrin is lacking, the skin becomes more vulnerable to dryness and irritation and allows allergens and irritants to penetrate more easily (1,2)

Patch testing is the only method capable of identifying the allergens responsible for their reactions and giving them a clear path toward relief

TLRs are expressed not only on immune cells, but also on non-immune cells such as vascular endothelial and smooth muscle cells, as well as on cells of the kidneys and nervous system, which are the three major target organs in hypertension

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