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Aspergillus cristatus attenuates DSS-induced intestinal barrier damage through reducing the oxidative stress, regulating short-chain fatty acid and inhibiting MAPK signaling pathways

The role of glutamine in cancer cell growth Rapidly proliferating cancer cells take up glutamine from plasma via various amino acid transporters, and then it is converted to glutamate in the mitochondria by the two forms of glutaminase: kidney-type glutaminase (GLS)1 and liver-type GLS2 8

An altered microbiota (gut dysbiosis) is a central mechanism implicated in the pathogenesis of IBD

This interaction disrupts SLIT2-ROBO4 signaling, skewing the senescent microenvironment toward pro-inflammatory dominance