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Its compact tripeptide structure ensures rapid diffusion into fibroblast, keratinocyte, and endothelial models, while its copper chelate enables robust activation of lysyl oxidase and superoxide dismutase

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Chronically high glucocorticoid levels induce neuronal atrophy and inhibit neurogenesis and synaptic plasticity in the hippocampus and prefrontal cortex, whereas excess IL-1 reduces BDNF production, collectively contributing to a depressed mood [306,307,308]