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Virtual clinical trial revealed that WT-based dosing strategy has a higher risk of SOS than age-based dosing strategy

Aucune toxicit n'a t mise en vidence dans les essais contrls, et les effets indsirables rapports se limitent des troubles digestifs lgers et transitoires

Upon failure of second-line treatment regimens, levofloxacin-containing therapies avoid the use of clarithromycin and are often the regimen selected in salvage therapy

Wang H, Chen Y, Lv J, Cheng X, Cao Q, Wang D, Zhang L, Zhu B, Shen M, Xu C, Xun M, Wang Z, Tang H, Hu S, Cui C, Jiang L, Yin Y, Guo L, Zhou Y, Han L, Gao Z, Zhang J, Yu S, Gao K, Wang J, Chen B, Wang W, Chen Z-Y, Li H, Shu Y (2024) Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results