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Nrf2 is an important component of the cellular defense against various exogenous and endogenous stresses that can be activated in response to a series of oxidative and electrophilic stimulations (Zhu et al., 2014)

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doi: 10.3390/ijms24098065 141 SubramaniamSKothariHBosmannM

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N-acetylcysteine N-acetylcysteine (NAC), another precursor to glutathione, is a prescription drug used to treat acetaminophen overdoses and as a mucolytic for muco-obstructive lung diseases [45]

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Lipid peroxidation relies heavily on polyunsaturated fatty acids (PUFAs) as fundamental reactants, and there is evidence of heightened consumption and metabolism of PUFAs, specifically, arachidonic acid (AA) and adrenic acid (AdA) are prominent in the neural tissues of those suffering from Alzheimers disease (Czapski et al., 2016)

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