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However, oral supplementation may be limited by: Gastrointestinal intolerance Malabsorption syndromes Nausea or reduced appetite Medication-related absorption changes IV B-complex: Bypasses gastrointestinal absorption Allows predictable uptake Can be combined with hydration and other supportive nutrients May be considered when oral options are ineffective or poorly tolerated When B-Complex IV Therapy May Be Appropriate B-complex IV therapy is not intended for routine or indefinite use

However, it should be noted that CXCR2 inhibition triggers side effects similar to those exhibited by the use of glucocorticoids, such as promoting bacterial/fungal infection and delaying wound healing