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[18] General adverse effects reported with hydrochlorothiazide include muscle spasm (muscle cramps), impotence (erectile dysfunction), fever, and weakness

For instance, a case series involving 12 women with interstitial cystitis reported symptom improvement after bladder-wall injections of BPC-157, yet the study lacked placebo controls, long-term follow-up, and was published in a non-indexed, alternative medicine journal