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Phil Trans R Soc B 375:20190404

Its regulation of microRNA expression provides additional therapeutic action in neurological disorders

This inhibition preserves cellular NAD+ levels, enhancing mitochondrial function, improving fat oxidation, and supporting overall metabolic health

JAVELIN Renal 100 (NCT02493751) is a phase 1b study aiming to evaluate safety, pharmacokinetics, and pharmacodynamics of avelumab (anti-PD-L1) plus axitinib (VEGFR TKI) therapy [96]