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The search details are shown in Supplementary Table 1, meantime the inclusion criteria were as follows: (i) patients with PCOS, (ii) patients with the treatment of carnitine supplementation, (iii) patients with body weight information, (iv) patients with exact doses and durations of carnitine supplementation, and (v) patients with the control group

When the level is low, the plasma/urine carnitine, plasma acylcarnitine profile, and urine organic acids in mothers of these infants should be evaluated since the primary or secondary carnitine deficiency could be caused by a maternal disorder (Longo et al., 2016)