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Results: Our analysis demonstrates that bilirubin directly neutralizes reactive species, preserves mitochondrial integrity, and promotes an anti-inflammatory milieu by inducing M2 microglia and modulating T-cell populations

For confirmed MCAS or significant mast cell reactivity, to support healthy mast cell stability directly

In the positive control PD model for the SH-SY5Y cell line, an elevation in antioxidant response element activity was accompanied by the up-regulation of proteins associated with the p62/Nrf2/Keap1 signaling pathway