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Thus, replenishment of metabolic intermediates via the TCA cycle is vital to cancer cells, making them reliant on glutamine, a phenomenon called anaplerosis 8

(2026) ( b ) Total cell recovery by organ in millions as determined by manual counting with a hemocytometer and staining with trypan blue

Since p75NTR / mice did not show any alteration regarding the course of de- and remyelination or glial reactions it is obvious that p75NTR does not play a major role in the induction of apoptosis in the cuprizone model

Consistent with the results of mRNA expression, we also found that the protein levels of vimentin, snail-1, snail-2, N-cadherin were also significantly negatively regulated, while the epithelial marker E-cadherin was positively regulated, indicating that Tim-AIII suppressed the EMT of NSCLC cells ( Fig