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[2] Patients should contact their GP if they experience: Side effects from B12 injections (though these are rare and usually mild) Difficulty attending scheduled injection appointments, as missed doses may lead to symptom recurrence New symptoms developing during treatment Concerns about treatment effectiveness or duration Changes in other medications that might affect B12 absorption Suspected adverse reactions to B12 treatment can be reported through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

Of note, I have fibromyalgia and an autoimmune disease (ankylosing spondylitis)

From the start of menstrual bleeding to ovulation the follicular phase estrogen levels tend to be higher than progesterone levels

If a doctor prescribes B12 injections, symptoms like fatigue, weakness, depression, and more may resolve within generally resolve in six to 12 weeks