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doi:10.1002/1098-2779(2000)6:3 3.0.Co;2-m Kasparek T, Theiner P, Filova A

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Clinical studies also showed that the selective 5-HT 3 antagonist, ondansetron, reduced the incidence and severity of antipsychotic-induced EPS in the schizophrenia treatment ( 5-HT 6 receptors are highly expressed in the basal ganglia (e.g., striatum), as well as the limbic (e.g., olfactory tubercles and hippocampus) and cortical regions ( 6 antagonist, SB-258585, alleviated haloperidol-induced bradykinesia and catalepsy ( 6 receptors is at least partly involved in alleviating EPS

[PUBMED Abstract] Forestier E, Schmiegelow K