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However, a much repeated criticism of studies of MSG taken without food is that the characteristic strong flavor of MSG is difficult to mask, unblinding the subjects to its identity and potentially leading to bias. Even in people who self-identify as MSG sensitive, studies have failed to provide reproducible evidence of an MSG effect. The authors of the largest and most comprehensive of such studies concluded that large doses of MSG given without food may elicit more symptoms than a placebo in individuals who believe that they react adversely to MSG

Nicola Cirillo and Richard Dean writing in The Lancet stated: 'As of March 21, the Yellow Card-reported frequency of facial paralysis or paresis and facial nerve disorder after any dose was close to 23 per million with the Pfizer-BioNTech vaccine and 13 per million with the Oxford-AstraZeneca vaccine

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