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Based on this, and the fact that the gut modulates the metabolism and vice versa we evaluated the bacterial composition of the fecal gut microbiome in our PD mouse models (P479L rotenone experiment at day 32, Wt+R+E experiment at day 62, PARK2 vs Wt, PARK2+V vs PARK2+E, PARK2+V vs PARK2+R at day 32, and PARK2+R+E at day 54 experiment) using taxonomic marker gene sequencing (16S rRNA gene)

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Maintaining a stable weight and healthy lifestyle is crucial for both procedures

For supplement brands, the key point is that their material properties demand different dosage-form decisions, release tests, and stability controls