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Under normal conditions, it exists in a benign, non-invasive budding yeast form, held in check by competing beneficial bacteria (predominantly Lactobacillus and Bifidobacterium species), a functional gut immune barrier, and adequate nutritional status

4.2 Sleep disruption contributes to dysregulated brain redox and altered metabolism: a bidirectional relationship dictating longevity and neurodegeneration Sleep plays an essential role in energy optimization and replenishing carbon sources not only for the brain but at a systematic level

While only minimal amount of apoptosis upon treatment with Ru(II)-OH or NP2 was observed, the treatment with NP4 trigger high amounts of early and late apoptotic processes (flow cytometry plots: Fig

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