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(8) M P Baar, R MC Brandt, D A Putavet, J DD Klein, et al (2017) Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging Cell, 2017 Mar 23, Volume 169 (Issue 1), Pages 132147.e16

NeuroImage 86 , 1018 (2014)

Injection of FOXO4-DRI in both naturally aged and induced-aging mice suppressed aortic aging and improved aortic function while alleviating endothelial cell senescence (PMID: 41625068)

Despite these promising findings, current evidence is preliminary, and the mechanistic basis for any comparative or synergistic advantages remains speculative