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Additionally, it exerts a highly favourable effect on diabetes prevention in individuals with prediabetes (HR: 0.07 compared to placebo)41 (Table 1)

The authors would like to gratefully acknowledge the training and use of mass spectrometry instrumentation provided by Professor Perdita Barrans group at the Michael Barber centre for collaborative mass spectrometry (MBCCMS) based at the University of Manchester

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For investigational compounds such as retatrutide, reconstitution instructions are specified in the trial protocol and IMPD, and are followed by trained trial site staff