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DAA in ALS Transcriptome analyses have identified distinct DAAs in postmortem samples from both sporadic and familial ALS cases (Pineda et al., 2024)

Subsequently, all hmmsearch hits with a sequence score of less than 100 were removed from further analysis

Common Xenobiotic Induction Pathways and Effect On Liver Morphology Induction Involving Constitutive Androstane Receptor Barbiturates and chemicals that induce CYP2B initially interact with the constitutive androstane receptor (CAR) that translocates to the nucleus and dimerizes with the retinoid-X-receptor (RXR)

Nuclear respiratory factor-1 (NRF1) induction drives mitochondrial biogenesis and attenuates amyloid beta-induced mitochondrial dysfunction and neurotoxicity