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This trait is often associated with changes in the epigenetic status of the cancerous cells, at different levels such as DNA and histone methylation, rRNA and tRNA methylation, chromatin remodeling and methylation-dependent regulation of non-coding RNAs

Research has also suggested that exercise can reduce oxidative stress by increasing glutathione levels

95% CI 1.03-3.31) independently predicted AKD

doi: 10.3389/fonc.2022.997919 Received 19 July 2022 Accepted 28 November 2022 Published 19 January 2023 Volume 12 - 2022 Edited by Cinzia Domenicotti, Universit di Genova, Italy Reviewed by Barbara Marengo, University of Genoa, Italy