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It plays a central role in mitochondrial energy metabolism as an electron carrier in the respiratory chain (complexes I and III)

World Psychiatry 22 , 129149 (2023)

These patterns are consistent with the progressive establishment of HBV infection in the liver during the natural history of HBV infection, with transition from individual hepatocytes producing virus and SVP to clusters of infected cells, which include hepatocytes containing only integrated HBV DNA and producing only SVP