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This activation induced the expression of pro-fibrotic genes such as -smooth muscle actin and fibronectin, leading to TM fibrosis and obstructed aqueous humor outflow (Wan et al., 2021

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M., Brni, M., Orlien, V., Trujillo, F

The pronounced similarity between anemia caused by hematopoietic Gpx4 -deficiency and -thalassemia raises the question whether underlying pathogenic principles are shared between both conditions