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Consistent with these findings, recent reviews have identified recurring antiviral mechanisms among carbon-dot-based nanomaterials, including viral surface protein interference and redox-mediated viral inactivation, however, they also emphasis the lack of standardised synthesis, limited in vivo validation, and incomplete toxicological characterisation, which collectively constraint clinical translation [131]

Researchers could collect: The exact diagnosis or reason for treatment Age and relevant health history The exact product and source Dose, route, and duration Other treatments being used at the same time Baseline pain and function scores Imaging when appropriate Standardized follow-up measurements Adverse events Reasons for discontinuation Outcomes at three, six, and 12 months Now imagine doing that with several thousand people