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Hydrogen sulfide poisoning

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To address these gaps, the field is moving toward integrated pipelines that combine multi-omics (genomics, transcriptomics, metabolomics), cell-based functional assays, and high-content imaging with standardized toxicology platforms that test multiple exposure concentrations, time points, and relevant cell types (keratinocytes, fibroblasts, endothelial cells, and immune populations) (Wang, et al., 2024)

Hence, there is a good correlation between in vivo sensitizing capacity and lysine peptide reactivity for these compounds