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For postgraduate study, Pauling went to the California Institute of Technology (Caltech), which provided a stipend for research and teaching

Citation43 In a study by Sang et al using in vitro experiments with LPS-stimulated ML-12 cells, Quercetin was found to modulate the SIRT1/AMPK pathway to inhibit both endoplasmic reticulum stress and oxidative stress levels in cells, which was manifested by a decrease in the expression of PDI, CHOP, GPC78, ATF6, PERK, and IRE1A, together with enhanced mitochondrial function, and increased levels of matrix metalloproteinase (MMP) and superoxide dismutase (SOD) while reducing the production of ROS and MDA, which in turn reduced the release of inflammatory factors in the cells

Why it Matters: increases the skin's moisture and could potentially delay the formation of wrinkles