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Figure 1 Evidence-based effects of key nutrients After understanding the pathological connection between nutrients and OA and discovering the significant role of the metabolism-inflammation-oxidative stress network in it, this study explores key nutrients that can prevent or treat OA through evidence-based medicine and reveals the mechanisms by which they exert preventive or therapeutic effects (Table 1)

Regulating autophagy facilitated therapeutic efficacy of the sonic Hedgehog pathway inhibition on lung adenocarcinoma through GLI2 suppression and ROS production

however, studies investigating the switch from the originator to the biosimilar in patients with HS are lacking

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