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Ferroptosis induces morphological changes that manifest as smaller mitochondria, increased mitochondrial membrane density, decreased or lack of mitochondrial cristae, and outer membrane breaks (2)

In addition, curcumin positively affects body weight and glucose, increases GPx activity (165), and decreases FFA, triglycerides, and cholesterol concentrations in diabetic rats ( Berberine (5,6-dihydro-9,10-dimethoxybenzo [g]-1,3-benzodioxolo [5,6-a] quinolizinium) is a plant alkaloid found and derived from numerous families of plants, such as Annonaceae, Menispermaceae, Papaveraceae, Ranunculaceae , etc

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