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Although their mechanisms of action remain incompletely understood, the damage and repair effects of astrocytes in stroke pathology make them a significant target for stroke treatment (Patabendige et al., 2021)

Usually, multivariate discriminant algorithms (e.g., PLS-DA, support vector machine, random forest) are optimized and evaluated using internal figures of merit estimated by cross validation (CV) such as the area under the receiver operating characteristic curve (AUROC), sensitivity, specificity or accuracy to assess its discriminant performance

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In another study, a mouse model of Huntingtons disease (HD) underwent 12 weeks of treadmill exercise, 3 times a day