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Pena et al., 2011)

On the contrary, a quasi-total (excluding the neck and the head) exposure of human volunteers to a very low ozone concentration in a sauna cabin for 20 min results in a very transient increase of LOPs in the peripheral circulation that exerts therapeutic effects in chronic limb ischemia's patients [45, 46] interpreted as due to an induction of antioxidant enzymes and HO-1