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Antifibrotic Properties: Milk thistle affects the development of liver fibrosis, minimizing excessive scar tissue formation Enhances Bile Production : Milk thistle may enhance bile and bile acid excretion due to its high fiber content, which contributes to lowering cholesterol and triglyceride levels, with over 80% of the active compound being eliminated through bile

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In light of these risks, the AASM no longer recommends dopaminergic agents as first-line therapies in long-term management of RLS