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Inflammasome is a multi-protein complex assembled by natural immune recognition receptors in the cytoplasm, which can mediate the production of various inflammatory mediators such as IL-1 and is crucial for the occurrence of inflammatory reactions (Li et al., 2020c)

Glutathione treatments are used for delivering a concentrated dose of glutathione, a powerful antioxidant, into the bloodstream for optimal absorption and effectiveness

Further functional studies and clinical applications of this polymorphism could significantly contribute to reducing HAPE incidence and improving preventive and therapeutic strategies