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reported that under high hydrostatic pressure, downregulation of cystathionine lyase/hydrogen sulfide (CSE/H 2 S) induce ferroptosis thereby exacerbating VSMC dysfunction

The strategy of wrapping extracellular vesicles can not only effectively protect proteins from the degradation of proteases in the blood and the phagocytosis of phagocytes, but also help to penetrate the barrier of the cell membrane (136)

It is required for mitochondrial energy metabolism, normal nervous system function, red blood cell development and maturation, DNA synthesis and the methylation cycle, and has antioxidant effects at the cellular level

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