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[DOI] [PubMed] [Google Scholar] 4.Sikiri P, Petek M, Rucman R, Seiwerth S, Grabarevi Z, Rotkvi I, et al

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These are released from the kidney and lungs, respectively, and ultimately result in increased angiotensin II, which has been shown to trigger ROS formation in vascular smooth muscle cells, which inhibits NO and cGMP, contributing to vasoconstriction