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(2006a, b) demonstrated the role of Comano thermal water in the significant inhibition of intracellular TNF-alpha, resulting in the downregulation of IL-8 and IL-6 in keratinocytes, which ultimately led to the control of the abnormal differentiation of keratinocytes, opening ways to treat skin diseases with underlying abnormal differentiation of keratinocytes

In fact, they are part of what scientists call the "Antioxidant Regeneration Cycle." When an antioxidant like Vitamin C neutralises a free radical, it becomes "oxidised" or spent

Works well for skin that feels dull, rough, or in need of a refreshing wash

Cui et al., 2021