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This objective was pursued to further understand the role of mitochondrial dysfunction in the persistence of fatigue symptoms in long COVID, providing insights into potential diagnostic and therapeutic strategies

9 Pathologies like Alzheimers disease seem to be correlated with an initial peak of locally produced IGF-1 that putatively aims to maintain homeostasis in front of IGF-1 receptor hypo-response, eventually leading to functional exhaustion and hypo-production of IGF-1

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