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Some of the first symptoms of a metabolic crisis are: extreme sleepiness behavior changes irritable mood poor appetite Other symptoms then follow: fever nausea diarrhea vomiting hypoglycemia If a metabolic crisis is not treated, a child with CTD can develop: breathing problems swelling of the brain seizuresThese are also called "convulsions" or "fits." During a seizure, a person loses consciousness and control of his or her muscles

Hamidinejat, H., Ghorbanpour, M., Nabavi, L., Hajikolaie, M

Gataullina, S

Cells transfected with pEX-GFP-hLC3WT were selected with G418 for use as permanent clones of GFP-hLC3WT overexpression