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6), 25% concentrated WRNE media (cWRNE) consisting of advanced DMEM/F12 supplemented with penicillin/streptomycin (1% v/v), GlutaMAX (1% v/v), 25% (v/v) L-WRN conditioned medium 61 concentrated using 10 kDa Amicon Ultra filter unit (Merck, #UFC901008), murine EGF (50 ng/mL), 1X N2 supplement, 1X B27 supplement, N-acetyl-L cysteine (1 mM

Based on these data, we propose that by directly targeting SOX2 + cells within the tissue or by isolating and expanding these cells for transplantation and activation, we might regenerate the secretory units of salivary glands and return quality of life to the patients following irradiation therapy

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Liposomal formulations may improve penetration and stability